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Keiichi Higuchi Selected Research

mouse amyloidogenic apolipoprotein A-II

7/2007Amyloidosis in transgenic mice expressing murine amyloidogenic apolipoprotein A-II (Apoa2c).
5/2004Tissue distribution, biochemical properties, and transmission of mouse type A AApoAII amyloid fibrils.

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Keiichi Higuchi Research Topics

Disease

33Amyloidosis
01/2022 - 09/2002
10Amyloid Plaque
10/2018 - 09/2002
5Alzheimer Disease (Alzheimer's Disease)
08/2014 - 01/2002
4Cataract (Cataracts)
01/2022 - 02/2006
4Inflammation (Inflammations)
01/2018 - 07/2008
3Neoplasms (Cancer)
01/2022 - 02/2006
2Atrophy
08/2017 - 04/2013
2Type 2 Diabetes Mellitus (MODY)
01/2017 - 11/2014
2Transthyretin-Related Hereditary Amyloidosis
04/2016 - 08/2011
2Proteostasis Deficiencies
06/2012 - 05/2010
2Prion Diseases (Transmissible Spongiform Encephalopathies)
07/2007 - 11/2002
1Macular Degeneration (Age-Related Maculopathy)
10/2018
1Atherosclerosis
10/2018
1Disease Progression
10/2018
1Acute-Phase Reaction
01/2018
1Rupture
03/2017
1Obesity
01/2017
1Body Weight (Weight, Body)
01/2017
1Breast Neoplasms (Breast Cancer)
06/2016
1Lymphatic Metastasis
06/2016
1Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy)
04/2016
1familial visceral Amyloidosis
01/2015
1Oculocutaneous albinism type 2
01/2015
1Oculocutaneous Albinism (Albinism, Yellow Mutant)
01/2015
1Polyuria
11/2014
1Heart Failure
07/2014
1Atrial Fibrillation
07/2014
1Cardiac Arrhythmias (Arrythmia)
07/2014
1Hearing Loss (Hearing Impairment)
06/2014
1Myofibrillar Myopathy
04/2013
1Hereditary Sensory and Motor Neuropathy (Dejerine Sottas Disease)
04/2013
1Osteoporosis
04/2013
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
06/2012
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
06/2012
1Dementia (Dementias)
06/2012
1Huntington Disease (Huntington's Disease)
06/2012
1Parkinson Disease (Parkinson's Disease)
06/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
06/2012
1Tauopathies
06/2012

Drug/Important Bio-Agent (IBA)

28Amyloid (Amyloid Fibrils)IBA
01/2021 - 09/2002
21Apolipoprotein A-II (Apolipoprotein A2)IBA
01/2022 - 09/2002
14Proteins (Proteins, Gene)FDA Link
01/2022 - 09/2002
5Amyloidogenic ProteinsIBA
04/2021 - 09/2002
5Prealbumin (Transthyretin)IBA
03/2017 - 06/2004
4AA amyloidosisIBA
01/2018 - 07/2007
3Lipoproteins (Lipoprotein)IBA
10/2018 - 06/2010
3Glucose (Dextrose)FDA LinkGeneric
01/2017 - 11/2014
3ApolipoproteinsIBA
01/2017 - 01/2002
3Peptides (Polypeptides)IBA
02/2015 - 09/2009
2Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)IBA
01/2022 - 07/2013
2LipidsIBA
10/2018 - 01/2017
2Serum Amyloid A Protein (Serum Amyloid A)IBA
01/2018 - 06/2016
2Messenger RNA (mRNA)IBA
06/2016 - 03/2015
2PrionsIBA
06/2012 - 05/2006
2mouse amyloidogenic apolipoprotein A-IIIBA
07/2007 - 05/2004
2CholesterolIBA
04/2007 - 02/2006
2lanosterol synthaseIBA
04/2007 - 02/2006
1p38 Mitogen-Activated Protein KinasesIBA
01/2022
1Keratins (Keratin)IBA
01/2022
1Transcription Factors (Transcription Factor)IBA
01/2022
1Crystallins (Crystallin)IBA
01/2022
1Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
04/2021
1AntibodiesIBA
04/2021
1CurcuminIBA
01/2021
1Drinking WaterIBA
01/2019
1acetovanillone (apocynin)IBA
01/2019
1tempolIBA
01/2019
1HDL LipoproteinsIBA
01/2018
1lipopigmentsIBA
08/2017
1Fatty Acids (Saturated Fatty Acids)IBA
01/2017
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2017
1coenzyme Q10 (CoQ10)IBA
01/2017
1Biological ProductsIBA
01/2017
1Progesterone Receptors (Progesterone Receptor)IBA
06/2016
1Biomarkers (Surrogate Marker)IBA
06/2016
1Acute-Phase Proteins (Acute-Phase Protein)IBA
06/2016
1Coloring Agents (Dyes)IBA
06/2016
1Estrogen ReceptorsIBA
06/2016
1Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2015
1NucleotidesIBA
01/2015
1Fibrinogen (Factor I)FDA Link
01/2015
1Sodium-Glucose Transporter 2 InhibitorsIBA
11/2014
1Sirtuin 3IBA
06/2014
1Sirtuin 1IBA
06/2014
1ubiquinol-10IBA
06/2014
1EnzymesIBA
07/2013
1Oxidoreductases (Dehydrogenase)IBA
07/2013
1coproporphyrinogen IIIIBA
07/2013
1Heme (Haem)IBA
07/2013
14-(4-sulfophenylazo)-2-mercuriphenol (SAMP)IBA
04/2013
1polyglutamineIBA
06/2012
1Superoxide Dismutase-1IBA
06/2012
1SynucleinsIBA
06/2012
1Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
08/2011
1Heparin (Liquaemin)FDA LinkGeneric
08/2011
1Apolipoprotein A-I (Apolipoprotein A1)IBA
08/2011

Therapy/Procedure

5Therapeutics
01/2018 - 05/2006
2Lenses
01/2022 - 02/2006
2Caloric Restriction
03/2017 - 01/2017
2Liver Transplantation
03/2017 - 04/2016